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HLA-Arena: A Customizable Environment for the Structural Modeling and Analysis of Peptide-HLA Complexes for Cancer Immunotherapy
PURPOSE: HLA protein receptors play a key role in cellular immunity. They bind intracellular peptides and display them for recognition by T-cell lymphocytes. Because T-cell activation is partially driven by structural features of these peptide-HLA complexes, their structural modeling and analysis ar...
Autores principales: | Antunes, Dinler A., Abella, Jayvee R., Hall-Swan, Sarah, Devaurs, Didier, Conev, Anja, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397777/ https://www.ncbi.nlm.nih.gov/pubmed/32667823 http://dx.doi.org/10.1200/CCI.19.00123 |
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