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Recombinant Human Plasma Gelsolin Improves Survival and Attenuates Lung Injury in a Murine Model of Multidrug-Resistant Pseudomonas aeruginosa Pneumonia

BACKGROUND: Plasma gelsolin (pGSN) is an abundant circulating protein quickly consumed by extensive tissue damage. Marked depletion is associated with later poor outcomes in diverse clinical circumstances. Repletion with recombinant human (rhu)–pGSN in animal models of inflammation lessens mortality...

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Detalles Bibliográficos
Autores principales:	DiNubile, Mark J, Levinson, Susan L, Stossel, Thomas P, Lawrenz, Matthew B, Warawa, Jonathan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Major Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397834/ https://www.ncbi.nlm.nih.gov/pubmed/32766380 http://dx.doi.org/10.1093/ofid/ofaa236

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