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Collapse of the hepatic gene regulatory network in the absence of FoxA factors

The FoxA transcription factors are critical for liver development through their pioneering activity, which initiates a highly complex regulatory network thought to become progressively resistant to the loss of any individual hepatic transcription factor via mutual redundancy. To investigate the disp...

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Detalles Bibliográficos
Autores principales: Reizel, Yitzhak, Morgan, Ashleigh, Gao, Long, Lan, Yemin, Manduchi, Elisabetta, Waite, Eric L., Wang, Amber W., Wells, Andrew, Kaestner, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397852/
https://www.ncbi.nlm.nih.gov/pubmed/32561546
http://dx.doi.org/10.1101/gad.337691.120