Identification of a localized nonsense-mediated decay pathway at the endoplasmic reticulum

Nonsense-mediated decay (NMD) is a translation-dependent RNA quality control mechanism that occurs in the cytoplasm. However, it is unknown how NMD regulates the stability of RNAs translated at the endoplasmic reticulum (ER). Here, we identify a localized NMD pathway dedicated to ER-translated mRNAs...

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Detalles Bibliográficos
Autores principales: Longman, Dasa, Jackson-Jones, Kathryn A., Maslon, Magdalena M., Murphy, Laura C., Young, Robert S., Stoddart, Jack J., Hug, Nele, Taylor, Martin S., Papadopoulos, Dimitrios K., Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397857/
https://www.ncbi.nlm.nih.gov/pubmed/32616520
http://dx.doi.org/10.1101/gad.338061.120

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