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Pancreatic cancer resistance conferred by stellate cells: looking for new preclinical models

Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor response to chemo- and (modest-dose conventionally fractionated) radio-therapy. Emerging evidence suggests that pancreatic stellate cells (PSCs) secrete deoxycytidine, which confers resistance to gemcitabine. In particular, deoxycytidine...

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Detalles Bibliográficos
Autores principales:	Che, Pei Pei, Gregori, Alessandro, Firuzi, Omidreza, Dahele, Max, Sminia, Peter, Peters, Godefridus J., Giovannetti, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398063/ https://www.ncbi.nlm.nih.gov/pubmed/32775041 http://dx.doi.org/10.1186/s40164-020-00176-0

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