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Assessment of statistical methods from single cell, bulk RNA-seq, and metagenomics applied to microbiome data
BACKGROUND: The correct identification of differentially abundant microbial taxa between experimental conditions is a methodological and computational challenge. Recent work has produced methods to deal with the high sparsity and compositionality characteristic of microbiome data, but independent be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398076/ https://www.ncbi.nlm.nih.gov/pubmed/32746888 http://dx.doi.org/10.1186/s13059-020-02104-1 |