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Prostaglandin E(2) stimulates the epithelial sodium channel (ENaC) in cultured mouse cortical collecting duct cells in an autocrine manner

Prostaglandin E(2) (PGE(2)) is the most abundant prostanoid in the kidney, affecting a wide range of renal functions. Conflicting data have been reported regarding the effects of PGE(2) on tubular water and ion transport. The amiloride-sensitive epithelial sodium channel (ENaC) is rate limiting for...

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Detalles Bibliográficos
Autores principales: Mansley, Morag K., Niklas, Christian, Nacken, Regina, Mandery, Kathrin, Glaeser, Hartmut, Fromm, Martin F., Korbmacher, Christoph, Bertog, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398144/
https://www.ncbi.nlm.nih.gov/pubmed/32442241
http://dx.doi.org/10.1085/jgp.201912525