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Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses
CD8(+) tissue-resident memory T cells (T(RM) cells) are poised at the portals of infection and provide long-term protective immunity. Despite their critical roles, the precise mechanics governing T(RM) cell reactivation in situ are unknown. Using a TCR-transgenic Nur77-GFP reporter to distinguish “a...
Autores principales: | Low, Jun Siong, Farsakoglu, Yagmur, Amezcua Vesely, Maria Carolina, Sefik, Esen, Kelly, Joseph B., Harman, Christian C.D., Jackson, Ruaidhri, Shyer, Justin A., Jiang, Xiaodong, Cauley, Linda S., Flavell, Richard A., Kaech, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398161/ https://www.ncbi.nlm.nih.gov/pubmed/32525985 http://dx.doi.org/10.1084/jem.20192291 |
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