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Talin1 controls dendritic cell activation by regulating TLR complex assembly and signaling

Talin critically controls integrin-dependent cell migration, but its regulatory role in skin dendritic cells (DCs) during inflammatory responses has not been investigated. Here, we show that talin1 regulates not only integrin-dependent Langerhans cell (LC) migration, but also MyD88-dependent Toll-li...

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Detalles Bibliográficos
Autores principales: Lim, Thomas Jun Feng, Bunjamin, Maegan, Ruedl, Christiane, Su, I-hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398162/
https://www.ncbi.nlm.nih.gov/pubmed/32438408
http://dx.doi.org/10.1084/jem.20191810