NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells

NKG2D is a danger sensor expressed on different subsets of innate and adaptive lymphocytes. Despite its established role as a potent activator of the immune system, NKG2D-driven regulation of CD4(+) T helper (Th) cell–mediated immunity remains unclear. In this study, we demonstrate that NKG2D modula...

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Detalles Bibliográficos
Autores principales: Babic, Marina, Dimitropoulos, Christoforos, Hammer, Quirin, Stehle, Christina, Heinrich, Frederik, Sarsenbayeva, Assel, Eisele, Almut, Durek, Pawel, Mashreghi, Mir-Farzin, Lisnic, Berislav, Van Snick, Jacques, Löhning, Max, Fillatreau, Simon, Withers, David R., Gagliani, Nicola, Huber, Samuel, Flavell, Richard A., Polic, Bojan, Romagnani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398170/
https://www.ncbi.nlm.nih.gov/pubmed/32453422
http://dx.doi.org/10.1084/jem.20190133

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