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Circulating tumor cells: Ready for translation?

Circulating tumor cells are tumor-derived pioneers responsible for the metastatic spread of cancer. Here, we outline recent discoveries, challenges, and future trends for circulating tumor cell investigations, arguing that the time is coming for translation of this work into clinical practice.

Detalles Bibliográficos
Autores principales: Diamantopoulou, Zoi, Castro-Giner, Francesc, Aceto, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398171/
https://www.ncbi.nlm.nih.gov/pubmed/32644115
http://dx.doi.org/10.1084/jem.20200356
Descripción
Sumario:Circulating tumor cells are tumor-derived pioneers responsible for the metastatic spread of cancer. Here, we outline recent discoveries, challenges, and future trends for circulating tumor cell investigations, arguing that the time is coming for translation of this work into clinical practice.