Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21

Recent studies indicate that cancer-associated fibroblasts (CAFs) are phenotypically and functionally heterogeneous. However, little is known about CAF subtypes, the roles they play in cancer progression, and molecular mediators of the CAF “state.” Here, we identify a novel cell surface pan-CAF mark...

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Detalles Bibliográficos
Autores principales: Hussain, Ali, Voisin, Veronique, Poon, Stephanie, Karamboulas, Christina, Bui, Ngoc Hoang Bao, Meens, Jalna, Dmytryshyn, Julia, Ho, Victor W., Tang, Kwan Ho, Paterson, Joshua, Clarke, Blaise A., Bernardini, Marcus Q., Bader, Gary D., Neel, Benjamin G., Ailles, Laurie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398174/
https://www.ncbi.nlm.nih.gov/pubmed/32434219
http://dx.doi.org/10.1084/jem.20191094

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