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C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway

BACKGROUND: The increased bone marrow angiogenesis is involved in the progression of multiple myeloma (MM) with the underlying mechanism poorly understood. Cancer-released exosomes could play an important role in the pathological angiogenesis through exosomal microRNAs (miRs) delivery. It is reporte...

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Detalles Bibliográficos
Autores principales:	Liu, Liping, Ye, Qinmao, Liu, Langni, Bihl, Ji Chen, Chen, Yanfang, Liu, Jing, Cheng, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398185/ https://www.ncbi.nlm.nih.gov/pubmed/32746845 http://dx.doi.org/10.1186/s12967-020-02468-9

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