CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice

BACKGROUND: Inhibition of CD4 T cells reduces stroke-induced infarction by inhibiting neuroinflammation in the ischemic brain in experimental stroke. Nevertheless, little is known about its effects on neuronal survival signaling pathways. In this study, we investigated the effects of CD4 T cell defi...

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Detalles Bibliográficos
Autores principales: Zhang, Hongfei, Xiong, Xiaoxing, Gu, Lijuan, Xie, Weiying, Zhao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398241/
https://www.ncbi.nlm.nih.gov/pubmed/32832192
http://dx.doi.org/10.1186/s41016-018-0140-9

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