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Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9
Production of IFN-γ is a key innate immune mechanism that limits replication of intracellular bacteria such as Francisella tularensis (Ft) until adaptive immune responses develop. Previously, we demonstrated that the host cell types responsible for IFN-γ production in response to murine Francisella...
Autores principales: | De Pascalis, Roberto, Rossi, Amy P., Mittereder, Lara, Takeda, Kazuyo, Akue, Adovi, Kurtz, Sherry L., Elkins, Karen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398525/ https://www.ncbi.nlm.nih.gov/pubmed/32745117 http://dx.doi.org/10.1371/journal.pone.0237034 |
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