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Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9

Production of IFN-γ is a key innate immune mechanism that limits replication of intracellular bacteria such as Francisella tularensis (Ft) until adaptive immune responses develop. Previously, we demonstrated that the host cell types responsible for IFN-γ production in response to murine Francisella...

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Detalles Bibliográficos
Autores principales: De Pascalis, Roberto, Rossi, Amy P., Mittereder, Lara, Takeda, Kazuyo, Akue, Adovi, Kurtz, Sherry L., Elkins, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398525/
https://www.ncbi.nlm.nih.gov/pubmed/32745117
http://dx.doi.org/10.1371/journal.pone.0237034

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