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Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila
Neurofibromatosis type 1 is a monogenetic disorder that predisposes individuals to tumor formation and cognitive and behavioral symptoms. The neuronal circuitry and developmental events underlying these neurological symptoms are unknown. To better understand how mutations of the underlying gene (NF1...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398555/ https://www.ncbi.nlm.nih.gov/pubmed/32697780 http://dx.doi.org/10.1371/journal.pgen.1008920 |