Developmental loss of neurofibromin across distributed neuronal circuits drives excessive grooming in Drosophila

Neurofibromatosis type 1 is a monogenetic disorder that predisposes individuals to tumor formation and cognitive and behavioral symptoms. The neuronal circuitry and developmental events underlying these neurological symptoms are unknown. To better understand how mutations of the underlying gene (NF1...

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Detalles Bibliográficos
Autores principales: King, Lanikea B., Boto, Tamara, Botero, Valentina, Aviles, Ari M., Jomsky, Breanna M., Joseph, Chevara, Walker, James A., Tomchik, Seth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398555/
https://www.ncbi.nlm.nih.gov/pubmed/32697780
http://dx.doi.org/10.1371/journal.pgen.1008920

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