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Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany
The COVID-19 pandemic has led to an unprecedented world-wide effort to gather data, model, and understand the viral spread. Entire societies and economies are desperate to recover and get back to normality. However, to this end accurate models are of essence that capture both the viral spread and th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398641/ https://www.ncbi.nlm.nih.gov/pubmed/32836600 http://dx.doi.org/10.1007/s00466-020-01883-5 |
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author | Kergaßner, Andreas Burkhardt, Christian Lippold, Dorothee Kergaßner, Matthias Pflug, Lukas Budday, Dominik Steinmann, Paul Budday, Silvia |
author_facet | Kergaßner, Andreas Burkhardt, Christian Lippold, Dorothee Kergaßner, Matthias Pflug, Lukas Budday, Dominik Steinmann, Paul Budday, Silvia |
author_sort | Kergaßner, Andreas |
collection | PubMed |
description | The COVID-19 pandemic has led to an unprecedented world-wide effort to gather data, model, and understand the viral spread. Entire societies and economies are desperate to recover and get back to normality. However, to this end accurate models are of essence that capture both the viral spread and the courses of disease in space and time at reasonable resolution. Here, we combine a spatially resolved county-level infection model for Germany with a memory-based integro-differential approach capable of directly including medical data on the course of disease, which is not possible when using traditional SIR-type models. We calibrate our model with data on cumulative detected infections and deaths from the Robert-Koch Institute and demonstrate how the model can be used to obtain county- or even city-level estimates on the number of new infections, hospitality rates and demands on intensive care units. We believe that the present work may help guide decision makers to locally fine-tune their expedient response to potential new outbreaks in the near future. |
format | Online Article Text |
id | pubmed-7398641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-73986412020-08-04 Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany Kergaßner, Andreas Burkhardt, Christian Lippold, Dorothee Kergaßner, Matthias Pflug, Lukas Budday, Dominik Steinmann, Paul Budday, Silvia Comput Mech Original Paper The COVID-19 pandemic has led to an unprecedented world-wide effort to gather data, model, and understand the viral spread. Entire societies and economies are desperate to recover and get back to normality. However, to this end accurate models are of essence that capture both the viral spread and the courses of disease in space and time at reasonable resolution. Here, we combine a spatially resolved county-level infection model for Germany with a memory-based integro-differential approach capable of directly including medical data on the course of disease, which is not possible when using traditional SIR-type models. We calibrate our model with data on cumulative detected infections and deaths from the Robert-Koch Institute and demonstrate how the model can be used to obtain county- or even city-level estimates on the number of new infections, hospitality rates and demands on intensive care units. We believe that the present work may help guide decision makers to locally fine-tune their expedient response to potential new outbreaks in the near future. Springer Berlin Heidelberg 2020-08-03 2020 /pmc/articles/PMC7398641/ /pubmed/32836600 http://dx.doi.org/10.1007/s00466-020-01883-5 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Kergaßner, Andreas Burkhardt, Christian Lippold, Dorothee Kergaßner, Matthias Pflug, Lukas Budday, Dominik Steinmann, Paul Budday, Silvia Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title | Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title_full | Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title_fullStr | Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title_full_unstemmed | Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title_short | Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany |
title_sort | memory-based meso-scale modeling of covid-19: county-resolved timelines in germany |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398641/ https://www.ncbi.nlm.nih.gov/pubmed/32836600 http://dx.doi.org/10.1007/s00466-020-01883-5 |
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