Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat

Body weight is regulated by interoceptive neural circuits that track energy need, but how the activity of these circuits is altered in obesity remains poorly understood. Here we describe the in vivo dynamics of hunger-promoting AgRP neurons during the development of diet-induced obesity in mice. We...

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Detalles Bibliográficos
Autores principales: Beutler, Lisa R, Corpuz, Timothy V, Ahn, Jamie S, Kosar, Seher, Song, Weimin, Chen, Yiming, Knight, Zachary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398661/
https://www.ncbi.nlm.nih.gov/pubmed/32720646
http://dx.doi.org/10.7554/eLife.55909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398661/
https://www.ncbi.nlm.nih.gov/pubmed/32720646
http://dx.doi.org/10.7554/eLife.55909

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