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Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat
Body weight is regulated by interoceptive neural circuits that track energy need, but how the activity of these circuits is altered in obesity remains poorly understood. Here we describe the in vivo dynamics of hunger-promoting AgRP neurons during the development of diet-induced obesity in mice. We...
Autores principales: | Beutler, Lisa R, Corpuz, Timothy V, Ahn, Jamie S, Kosar, Seher, Song, Weimin, Chen, Yiming, Knight, Zachary A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398661/ https://www.ncbi.nlm.nih.gov/pubmed/32720646 http://dx.doi.org/10.7554/eLife.55909 |
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