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Copolymer Composition and Nanoparticle Configuration Enhance in vitro Drug Release Behavior of Poorly Water-soluble Progesterone for Oral Formulations

HYPOTHESIS: Developing oral formulations to enable effective release of poorly water-soluble drugs like progesterone is a major challenge in pharmaceutics. Coaxial electrospray can generate drug-loaded nanoparticles of strategic compositions and configurations to enhance physiological dissolution an...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Zhang, Rui, Illangakoon, Upulitha Eranka, Harker, Anthony Henry, Thrasivoulou, Christopher, Parhizkar, Maryam, Edirisinghe, Mohan, Luo, C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398683/
https://www.ncbi.nlm.nih.gov/pubmed/32801695
http://dx.doi.org/10.2147/IJN.S257353