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Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53
Eukaryotic replication origins are licensed by the loading of the replicative DNA helicase, Mcm2-7, in inactive double hexameric form around DNA. Subsequent origin activation is under control of multiple protein kinases that either promote or inhibit origin activation, which is important for genome...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398698/ https://www.ncbi.nlm.nih.gov/pubmed/32701054 http://dx.doi.org/10.7554/eLife.58571 |