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Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole
PURPOSE: To summarize current surgical techniques for treating primary macular holes (MHs). METHODS: We reviewed publications detailing surgical approaches to primary MHs, briefly described their protocols, and outlined their results. RESULTS: Currently, the technique for primary MH repair is pars p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398756/ https://www.ncbi.nlm.nih.gov/pubmed/32801628 http://dx.doi.org/10.2147/OPTH.S262877 |
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author | Ittarat, Mantapond Somkijrungroj, Thanapong Chansangpetch, Sunee Pongsachareonnont, Pear |
author_facet | Ittarat, Mantapond Somkijrungroj, Thanapong Chansangpetch, Sunee Pongsachareonnont, Pear |
author_sort | Ittarat, Mantapond |
collection | PubMed |
description | PURPOSE: To summarize current surgical techniques for treating primary macular holes (MHs). METHODS: We reviewed publications detailing surgical approaches to primary MHs, briefly described their protocols, and outlined their results. RESULTS: Currently, the technique for primary MH repair is pars plana vitrectomy, removing the posterior cortical vitreous, stripping the epiretinal membranes, and ending with intraocular gas tamponade. The evident benefit of peeling off the internal limiting membrane (ILM) was clearly shown for MHs at stages 2 to 4 by achieving an anatomical closure rate of >90%, even in large MH up to 650 µm. Newer MH surgical techniques include modification of ILM flap techniques, placing an autologous scaffolding of tissue within the hole, and cell therapy has shown to increase the closure rate of large and chronic macular holes, resulting in modest functional improvement in complicated MHs. CONCLUSION: Since the turn of the century, the success rate of modern macular surgery has increased, even for large and chronic MHs. There seems to be no limit to novel concepts in MH surgery, which range from anatomical closure to those proposing natural restoration of visual function via stem cell therapy. |
format | Online Article Text |
id | pubmed-7398756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-73987562020-08-13 Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole Ittarat, Mantapond Somkijrungroj, Thanapong Chansangpetch, Sunee Pongsachareonnont, Pear Clin Ophthalmol Review PURPOSE: To summarize current surgical techniques for treating primary macular holes (MHs). METHODS: We reviewed publications detailing surgical approaches to primary MHs, briefly described their protocols, and outlined their results. RESULTS: Currently, the technique for primary MH repair is pars plana vitrectomy, removing the posterior cortical vitreous, stripping the epiretinal membranes, and ending with intraocular gas tamponade. The evident benefit of peeling off the internal limiting membrane (ILM) was clearly shown for MHs at stages 2 to 4 by achieving an anatomical closure rate of >90%, even in large MH up to 650 µm. Newer MH surgical techniques include modification of ILM flap techniques, placing an autologous scaffolding of tissue within the hole, and cell therapy has shown to increase the closure rate of large and chronic macular holes, resulting in modest functional improvement in complicated MHs. CONCLUSION: Since the turn of the century, the success rate of modern macular surgery has increased, even for large and chronic MHs. There seems to be no limit to novel concepts in MH surgery, which range from anatomical closure to those proposing natural restoration of visual function via stem cell therapy. Dove 2020-07-30 /pmc/articles/PMC7398756/ /pubmed/32801628 http://dx.doi.org/10.2147/OPTH.S262877 Text en © 2020 Ittarat et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Ittarat, Mantapond Somkijrungroj, Thanapong Chansangpetch, Sunee Pongsachareonnont, Pear Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title | Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title_full | Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title_fullStr | Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title_full_unstemmed | Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title_short | Literature Review of Surgical Treatment in Idiopathic Full-Thickness Macular Hole |
title_sort | literature review of surgical treatment in idiopathic full-thickness macular hole |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398756/ https://www.ncbi.nlm.nih.gov/pubmed/32801628 http://dx.doi.org/10.2147/OPTH.S262877 |
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