Current Overview on Hypercoagulability in COVID-19

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboem...

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Autores principales: Singhania, Namrata, Bansal, Saurabh, Nimmatoori, Divya P., Ejaz, Abutaleb A., McCullough, Peter A., Singhania, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Leading Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398761/
https://www.ncbi.nlm.nih.gov/pubmed/32748336
http://dx.doi.org/10.1007/s40256-020-00431-z
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author Singhania, Namrata
Bansal, Saurabh
Nimmatoori, Divya P.
Ejaz, Abutaleb A.
McCullough, Peter A.
Singhania, Girish
author_facet Singhania, Namrata
Bansal, Saurabh
Nimmatoori, Divya P.
Ejaz, Abutaleb A.
McCullough, Peter A.
Singhania, Girish
author_sort Singhania, Namrata
collection PubMed
description The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboembolic complications, especially in critically ill patients. The pathogenesis is likely due to endothelial injury, immobilization, and an increase in circulating prothrombotic factors. Data on treatment are limited, although prophylactic anticoagulation is advised in all hospitalized patients. Herein, we have comprehensively reviewed the current literature available on CAC and highlight the pathogenesis, clinical features, and management of CAC.
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spelling pubmed-73987612020-08-04 Current Overview on Hypercoagulability in COVID-19 Singhania, Namrata Bansal, Saurabh Nimmatoori, Divya P. Ejaz, Abutaleb A. McCullough, Peter A. Singhania, Girish Am J Cardiovasc Drugs Leading Article The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboembolic complications, especially in critically ill patients. The pathogenesis is likely due to endothelial injury, immobilization, and an increase in circulating prothrombotic factors. Data on treatment are limited, although prophylactic anticoagulation is advised in all hospitalized patients. Herein, we have comprehensively reviewed the current literature available on CAC and highlight the pathogenesis, clinical features, and management of CAC. Springer International Publishing 2020-08-04 2020 /pmc/articles/PMC7398761/ /pubmed/32748336 http://dx.doi.org/10.1007/s40256-020-00431-z Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Leading Article
Singhania, Namrata
Bansal, Saurabh
Nimmatoori, Divya P.
Ejaz, Abutaleb A.
McCullough, Peter A.
Singhania, Girish
Current Overview on Hypercoagulability in COVID-19
title Current Overview on Hypercoagulability in COVID-19
title_full Current Overview on Hypercoagulability in COVID-19
title_fullStr Current Overview on Hypercoagulability in COVID-19
title_full_unstemmed Current Overview on Hypercoagulability in COVID-19
title_short Current Overview on Hypercoagulability in COVID-19
title_sort current overview on hypercoagulability in covid-19
topic Leading Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398761/
https://www.ncbi.nlm.nih.gov/pubmed/32748336
http://dx.doi.org/10.1007/s40256-020-00431-z
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