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Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Relapses in multiple sclerosis can result in irreversible nervous system tissue injury. If these events could be detected early, targeted immunotherapy could potentially slow disease progression. We describe the use of engineered biomaterial-based immunological niches amenable to biopsy to provide i...

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Detalles Bibliográficos
Autores principales:	Morris, Aaron H., Hughes, Kevin R., Oakes, Robert S., Cai, Michelle M., Miller, Stephen D., Irani, David N., Shea, Lonnie D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398910/ https://www.ncbi.nlm.nih.gov/pubmed/32747712 http://dx.doi.org/10.1038/s41467-020-17629-z

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