Cargando…

Impact of vaccine type on HIV-1 vaccine elicited antibody durability and B cell gene signature

Efficacious HIV-1 vaccination requires elicitation of long-lived antibody responses. However, our understanding of how different vaccine types elicit durable antibody responses is lacking. To assess the impact of vaccine type on antibody responses, we measured IgG isotypes against four consensus HIV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palli, Rohith, Seaton, Kelly E., Piepenbrink, Michael S., Hural, John, Goepfert, Paul A., Laher, Fatima, Buchbinder, Susan P., Churchyard, Gavin, Gray, Glenda E., Robinson, Harriet L., Huang, Yunda, Janes, Holly, Kobie, James J., Keefer, Michael C., Tomaras, Georgia D., Thakar, Juilee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398916/ https://www.ncbi.nlm.nih.gov/pubmed/32747654 http://dx.doi.org/10.1038/s41598-020-69007-w

Ejemplares similares

Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens
por: Huang, Yunda, et al.
Publicado: (2022)

Cross-protocol assessment of induction and durability of VISP/R in HIV preventive vaccine trial participants
por: Espy, Nicole, et al.
Publicado: (2023)

Meta-analysis of HIV-1 vaccine elicited mucosal antibodies in humans
por: Seaton, Kelly E., et al.
Publicado: (2021)

Executable pathway analysis using ensemble discrete-state modeling for large-scale data
por: Palli, Rohith, et al.
Publicado: (2019)

Phase 2a safety and immunogenicity testing of DNA and recombinant modified vaccinia ankara virus vaccines expressing virus-like particles
por: Goepfert, P, et al.
Publicado: (2012)

Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells
por: Piepenbrink, Michael S., et al.
Publicado: (2019)

Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults
por: Buchbinder, Susan P., et al.
Publicado: (2017)

Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users
por: Piepenbrink, Michael S., et al.
Publicado: (2016)

Executable models of immune signaling pathways in HIV-associated atherosclerosis
por: Palshikar, Mukta G., et al.
Publicado: (2022)

Persistence of HIV-1 Env-Specific Plasmablast Lineages in Plasma Cells after Vaccination in Humans
por: Basu, Madhubanti, et al.
Publicado: (2020)

Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized Trials
por: Huang, Yunda, et al.
Publicado: (2015)

Durable Immunity to Ricin Toxin Elicited by a Thermostable, Lyophilized Subunit Vaccine
por: Novak, Hayley, et al.
Publicado: (2021)

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection
por: Ditse, Zanele, et al.
Publicado: (2020)

Assessing Durability of Vaccine Effect Following Blinded Crossover in COVID-19 Vaccine Efficacy Trials
por: Follmann, Dean, et al.
Publicado: (2020)

A Phase IIA Randomized Clinical Trial of a Multiclade HIV-1 DNA Prime Followed by a Multiclade rAd5 HIV-1 Vaccine Boost in Healthy Adults (HVTN204)
por: Churchyard, Gavin J., et al.
Publicado: (2011)

SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques
por: Garrido, Carolina, et al.
Publicado: (2021)

Molecular characterization of atherosclerosis in HIV positive persons
por: Cornwell, Adam, et al.
Publicado: (2021)

Uptake of Genital Mucosal Sampling in HVTN 097, a Phase 1b HIV Vaccine Trial in South Africa
por: Lazarus, Erica Maxine, et al.
Publicado: (2014)

Predictors of HVTN 503 MRK-AD5 HIV-1 gag/pol/nef Vaccine Induced Immune Responses
por: Hopkins, Kathryn L., et al.
Publicado: (2014)

Novel Sequence-Based Mapping of Recently Emerging H5NX Influenza Viruses Reveals Pandemic Vaccine Candidates
por: Anderson, Christopher S., et al.
Publicado: (2016)

Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters
por: Berry, Catherine, et al.
Publicado: (2023)

Benign ethnic neutropenia in a South African population, and its association with HIV acquisition and adverse event reporting in an HIV vaccine clinical trial
por: Mpofu, Rephaim, et al.
Publicado: (2021)

Profiles of Human Serum Antibody Responses Elicited by Three Leading HIV Vaccines Focusing on the Induction of Env-Specific Antibodies
por: Vaine, Michael, et al.
Publicado: (2010)

DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs
por: Cashman, Kathleen A., et al.
Publicado: (2017)

Continued Follow-Up of Phambili Phase 2b Randomized HIV-1 Vaccine Trial Participants Supports Increased HIV-1 Acquisition among Vaccinated Men
por: Moodie, Zoe, et al.
Publicado: (2015)

Risk Factors Associated with HIV Acquisition in Males Participating in HIV Vaccine Efficacy Trials in South Africa
por: Malahleha, Mookho, et al.
Publicado: (2023)

Effectiveness and Durability of the BNT162b2 Vaccine against Omicron Sublineages in South Africa
por: Collie, Shirley, et al.
Publicado: (2022)

Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial
por: Williams, WB, et al.
Publicado: (2012)

Review of preventative HIV vaccine clinical trials in South Africa
por: Laher, Fatima, et al.
Publicado: (2020)

Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques
por: Virnik, Konstantin, et al.
Publicado: (2013)

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
por: Mandolesi, Marco, et al.
Publicado: (2021)

Adenoviral-vectored epigraph vaccine elicits robust, durable, and protective immunity against H3 influenza A virus in swine
por: Petro-Turnquist, Erika, et al.
Publicado: (2023)

A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody
por: Nogales, Aitor, et al.
Publicado: (2018)

Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials
por: Fischinger, Stephanie, et al.
Publicado: (2021)

Broadly binding and functional antibodies and persisting memory B cells elicited by HIV vaccine PDPHV
por: Wang, Shixia, et al.
Publicado: (2022)

Targeting and vaccine durability are key for population-level impact and cost-effectiveness of a pox-protein HIV vaccine regimen in South Africa
por: Selinger, Christian, et al.
Publicado: (2019)

Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse
por: Kiebala, Michelle, et al.
Publicado: (2015)

Fc-Effector-Independent in vivo Activity of a Potent Influenza B Neuraminidase Broadly Neutralizing Antibody
por: Khalil, Ahmed M., et al.
Publicado: (2023)

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
por: Weidenbacher, Payton A.-B., et al.
Publicado: (2022)

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
por: Weidenbacher, Payton A.-B., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v74lsrbf0kbbtdl0eugsfran13