FLCN Regulates HIF2α Nuclear Import and Proliferation of Clear Cell Renal Cell Carcinoma

Aims and Hypothesis: This study aims to explore the specific molecular mechanism of folliculin (FLCN)-induced proliferation, migration, and invasion in clear cell renal cell carcinoma (ccRCC) and to investigate the relationship of FLCN and HIF2α. Folliculin was identified as a tumor suppressor gene....

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Detalles Bibliográficos
Autores principales: Zhao, Xuyang, Ma, Yadong, Cui, Jie, Zhao, Haiyang, Liu, Lei, Wang, Yueyuan, Min, Pengxiang, Zhang, Lin, Chen, Yongchang, Du, Jun, Zhang, Yujie, Gu, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399043/
https://www.ncbi.nlm.nih.gov/pubmed/32850947
http://dx.doi.org/10.3389/fmolb.2020.00121

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