TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients

Background: Head and neck squamous cell carcinoma (HNSCC) is usually associated to tobacco and alcohol consumption. Increased telomerase activity has been consistently detected in 80–90% of malignant tumors, including HNSCC. Mutations within the promoter region of telomerase reverse transcriptase (T...

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Detalles Bibliográficos
Autores principales: Arantes, Lidia Maria Rebolho Batista, Cruvinel-Carloni, Adriana, de Carvalho, Ana Carolina, Sorroche, Bruna Pereira, Carvalho, André Lopes, Scapulatempo-Neto, Cristovam, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399085/
https://www.ncbi.nlm.nih.gov/pubmed/32850388
http://dx.doi.org/10.3389/fonc.2020.01275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399085/
https://www.ncbi.nlm.nih.gov/pubmed/32850388
http://dx.doi.org/10.3389/fonc.2020.01275

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