Cargando…

Ultrarapid Delayed Rectifier K(+) Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Atrial fibrillation (AF) is the most common cardiac arrhythmia. About 5–15% of AF patients have a mutation in a cardiac gene, including mutations in KCNA5, encoding the K(v)1.5 α-subunit of the ion channel carrying the atrial-specific ultrarapid delayed rectifier K(+) current (I(Kur)). Both loss-of-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hilderink, Sarah, Devalla, Harsha D., Bosch, Leontien, Wilders, Ronald, Verkerk, Arie O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399090/ https://www.ncbi.nlm.nih.gov/pubmed/32850774 http://dx.doi.org/10.3389/fcell.2020.00536

Ejemplares similares

Human Sinoatrial Node Pacemaker Activity: Role of the Slow Component of the Delayed Rectifier K(+) Current, I(Ks)
por: Verkerk, Arie O., et al.
Publicado: (2023)

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual I(K1)
por: Meijer van Putten, Rosalie M. E., et al.
Publicado: (2015)

Carbamazepine Increases the Risk of Sudden Cardiac Arrest by a Reduction of the Cardiac Sodium Current
por: Jia, Lixia, et al.
Publicado: (2022)

Role of the rapid delayed rectifier K(+) current in human induced pluripotent stem cells derived cardiomyocytes
por: Deo, Makarand, et al.
Publicado: (2020)

Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome
por: Wilders, Ronald
Publicado: (2012)

Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp
por: Verkerk, Arie O., et al.
Publicado: (2017)

TRPV4 regulates osteoblast differentiation and mitochondrial function that are relevant for channelopathy
por: Acharya, Tusar Kanta, et al.
Publicado: (2023)

A single cell transcriptional roadmap of human pacemaker cell differentiation
por: Wiesinger, Alexandra, et al.
Publicado: (2022)

Bioengineering Approaches to Mature Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Sun, Xuetao, et al.
Publicado: (2017)

Excitation–contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes
por: Kane, Christopher, et al.
Publicado: (2015)

Disease Modifiers of Inherited SCN5A Channelopathy
por: Verkerk, Arie O., et al.
Publicado: (2018)

Circular RNA Expression for Dilated Cardiomyopathy in Hearts and Pluripotent Stem Cell–Derived Cardiomyocytes
por: Zhang, Yiyu, et al.
Publicado: (2021)

Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
por: Ye, Liang, et al.
Publicado: (2021)

When ultrarapid is ultrarapid: on importance of temporal precision in neuroscience of language
por: Shtyrov, Yury Y., et al.
Publicado: (2015)

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology
por: Devalla, Harsha D, et al.
Publicado: (2015)

A Brief Review of Current Maturation Methods for Human Induced Pluripotent Stem Cells-Derived Cardiomyocytes
por: Ahmed, Razan Elfadil, et al.
Publicado: (2020)

Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation
por: Ernst, Patrick, et al.
Publicado: (2023)

Hyperpolarization-Activated Current, I (f), in Mathematical Models of Rabbit Sinoatrial Node Pacemaker Cells
por: Verkerk, Arie O., et al.
Publicado: (2013)

Pacemaker Activity of the Human Sinoatrial Node: An Update on the Effects of Mutations in HCN4 on the Hyperpolarization-Activated Current
por: Verkerk, Arie O., et al.
Publicado: (2015)

Long QT Syndrome and Sinus Bradycardia–A Mini Review
por: Wilders, Ronald, et al.
Publicado: (2018)

The Action Potential Clamp Technique as a Tool for Risk Stratification of Sinus Bradycardia Due to Loss-of-Function Mutations in HCN4: An In Silico Exploration Based on In Vitro and In Vivo Data
por: Verkerk, Arie O., et al.
Publicado: (2023)

Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models
por: Li, Jiuru, et al.
Publicado: (2022)

Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

A Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes
por: Jones, Aled R., et al.
Publicado: (2016)

Three-Dimensional Poly-(ε-Caprolactone) Nanofibrous Scaffolds Promote the Maturation of Human Pluripotent Stem Cells-Induced Cardiomyocytes
por: Zhang, Mingming, et al.
Publicado: (2022)

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an MYH6 Head Domain Variant Associated With Hypoplastic Left Heart Syndrome
por: Kim, Min-Su, et al.
Publicado: (2020)

Scaffold-Mediated Developmental Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Are Preserved After External Support Removal
por: Li, Jun, et al.
Publicado: (2021)

Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Gilbert, Guillaume, et al.
Publicado: (2021)

The Antidepressant Paroxetine Reduces the Cardiac Sodium Current
por: Plijter, Ingmar S., et al.
Publicado: (2023)

IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency
por: Luo, Xiaojing, et al.
Publicado: (2020)

Single-cell transcriptomic profiling reveals specific maturation signatures in human cardiomyocytes derived from LMNB2-inactivated induced pluripotent stem cells
por: Wang, Jie, et al.
Publicado: (2022)

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias
por: Hoekstra, Maaike, et al.
Publicado: (2012)

K(V)4.3 Expression Modulates Na(V)1.5 Sodium Current
por: Portero, Vincent, et al.
Publicado: (2018)

Low pH Attenuates Apoptosis by Suppressing the Volume-Sensitive Outwardly Rectifying (VSOR) Chloride Current in Chondrocytes
por: Kittl, Michael, et al.
Publicado: (2022)

Aquaporin Channels in the Heart—Physiology and Pathophysiology
por: Verkerk, Arie O., et al.
Publicado: (2019)

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes
por: Schwach, Verena, et al.
Publicado: (2017)

Optimizing the Direction and Order of the Motion Unveiled the Ability of Conventional Monolayers of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Show Frequency-Dependent Enhancement of Contraction and Relaxation Motion
por: Izumi-Nakaseko, Hiroko, et al.
Publicado: (2020)

Stress and pluripotency
por: Tang, Bor L.
Publicado: (2014)

Naturally Engineered Maturation of Cardiomyocytes
por: Scuderi, Gaetano J., et al.
Publicado: (2017)

Inwardly Rectifying Potassium Channel Kir2.1 and its “Kir-ious” Regulation by Protein Trafficking and Roles in Development and Disease
por: Hager, Natalie A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_11f7ccpi0ar0jvd1btlarna4u9