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Ultrarapid Delayed Rectifier K(+) Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Atrial fibrillation (AF) is the most common cardiac arrhythmia. About 5–15% of AF patients have a mutation in a cardiac gene, including mutations in KCNA5, encoding the K(v)1.5 α-subunit of the ion channel carrying the atrial-specific ultrarapid delayed rectifier K(+) current (I(Kur)). Both loss-of-...
Autores principales: | Hilderink, Sarah, Devalla, Harsha D., Bosch, Leontien, Wilders, Ronald, Verkerk, Arie O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399090/ https://www.ncbi.nlm.nih.gov/pubmed/32850774 http://dx.doi.org/10.3389/fcell.2020.00536 |
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