Data on proteomic profiling of extracellular vesicles of Acholeplasma laidlawii strains with increased resistance to antibiotics of different classes - ciprofloxacin and tetracycline

To elucidate the regularities of adaptation of the representatives of class Mollicutes to antimicrobials and to identify the promising targets for eradication of mycoplasma infections and contaminations the comparative analysis of the molecular basis of bacterial resistance to antibiotics of differe...

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Detalles Bibliográficos
Autores principales: Mouzykantov, Alexey, Medvedeva, Elena, Baranova, Natalia, Chernova, Olga, Chernov, Vladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Proteomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399241/
https://www.ncbi.nlm.nih.gov/pubmed/32775567
http://dx.doi.org/10.1016/j.dib.2020.106049
Descripción
Sumario:To elucidate the regularities of adaptation of the representatives of class Mollicutes to antimicrobials and to identify the promising targets for eradication of mycoplasma infections and contaminations the comparative analysis of the molecular basis of bacterial resistance to antibiotics of different classes is needed. Previously, we presented the data on the whole-genome sequences of Acholeplasma laidlawii strains with different susceptibility to ciprofloxacin (GenBank: LXYB00000000.1), tetracycline (GenBank: NELO00000000.2) and melittin (GenBank: NELN00000000.2) as well as the data on cell and extracellular vesicle proteomes of melittin-resistant A. laidlawii strain [1]. The lists of extracellular vesicle proteins secreted by A. laidlawii strains with the increased resistance to ciprofloxacin (PG8R(10)) and tetracycline (PG8R(Tet)) are presented here. The vesicle proteome profiles were obtained by 1D SDS-PAGE and liquid chromatography-mass spectrometry.

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