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The classification and treatment strategies of post-esophagectomy airway-gastric fistula
BACKGROUND: Airway-gastric fistulas (AGFs) are rare but life-threatening complications after esophagectomy for esophageal cancer. Their effective and reasonable management is challenging and still controversial. This study reports the classification and management strategies of post-esophagectomy AG...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399427/ https://www.ncbi.nlm.nih.gov/pubmed/32802439 http://dx.doi.org/10.21037/jtd-20-284 |
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author | Wang, Changchun Li, Chengqiang Yang, Xun Mao, Weimin Jiang, Youhua Wu, Jie Zhao, Qiang Ji, Anqi Chen, Qixun Li, Hecheng Liu, Jinshi |
author_facet | Wang, Changchun Li, Chengqiang Yang, Xun Mao, Weimin Jiang, Youhua Wu, Jie Zhao, Qiang Ji, Anqi Chen, Qixun Li, Hecheng Liu, Jinshi |
author_sort | Wang, Changchun |
collection | PubMed |
description | BACKGROUND: Airway-gastric fistulas (AGFs) are rare but life-threatening complications after esophagectomy for esophageal cancer. Their effective and reasonable management is challenging and still controversial. This study reports the classification and management strategies of post-esophagectomy AGF based on a retrospective analysis of 26 cases in two large volume centers in China. METHODS: Between January 2000 and December 2017, 6,316 consecutive patients with esophageal carcinoma underwent esophagectomy. AGF was verified in 26 patients. The patients with AGF were divided into two types based on the anatomic characteristics of the fistula. Type I was characterized by the presence of fistula orifices in digestive tract that were higher than those in the airway and were treated with conservative management. Type II had both fistula orifices located on the same horizontal plane and were treated with surgical management. Pearson Chi-Square (R software) was used to compare mortality rates. RESULTS: From January 2000 and December 2017, 26 cases occurred AGF in 6,316 consecutive patients with esophageal carcinoma underwent esophagectomy and the incidence of AGF was 0.4%. Ten of 12 patients with type I AGF survived. Nine of 14 patients with type II AGF died. There was a significantly difference in the mortality rates between patients with AGF type I and II, which was 16.7% (2/12) and 64.3% (9/14) (χ(2)=6.003, P=0.014), respectively. CONCLUSIONS: AGF may be classified into two types according to the anatomic characteristics. Type I patients may be cured by conservative management and type II patients, require surgical intervention with pedicled tissues flap wrapping of the airway. |
format | Online Article Text |
id | pubmed-7399427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-73994272020-08-13 The classification and treatment strategies of post-esophagectomy airway-gastric fistula Wang, Changchun Li, Chengqiang Yang, Xun Mao, Weimin Jiang, Youhua Wu, Jie Zhao, Qiang Ji, Anqi Chen, Qixun Li, Hecheng Liu, Jinshi J Thorac Dis Original Article BACKGROUND: Airway-gastric fistulas (AGFs) are rare but life-threatening complications after esophagectomy for esophageal cancer. Their effective and reasonable management is challenging and still controversial. This study reports the classification and management strategies of post-esophagectomy AGF based on a retrospective analysis of 26 cases in two large volume centers in China. METHODS: Between January 2000 and December 2017, 6,316 consecutive patients with esophageal carcinoma underwent esophagectomy. AGF was verified in 26 patients. The patients with AGF were divided into two types based on the anatomic characteristics of the fistula. Type I was characterized by the presence of fistula orifices in digestive tract that were higher than those in the airway and were treated with conservative management. Type II had both fistula orifices located on the same horizontal plane and were treated with surgical management. Pearson Chi-Square (R software) was used to compare mortality rates. RESULTS: From January 2000 and December 2017, 26 cases occurred AGF in 6,316 consecutive patients with esophageal carcinoma underwent esophagectomy and the incidence of AGF was 0.4%. Ten of 12 patients with type I AGF survived. Nine of 14 patients with type II AGF died. There was a significantly difference in the mortality rates between patients with AGF type I and II, which was 16.7% (2/12) and 64.3% (9/14) (χ(2)=6.003, P=0.014), respectively. CONCLUSIONS: AGF may be classified into two types according to the anatomic characteristics. Type I patients may be cured by conservative management and type II patients, require surgical intervention with pedicled tissues flap wrapping of the airway. AME Publishing Company 2020-07 /pmc/articles/PMC7399427/ /pubmed/32802439 http://dx.doi.org/10.21037/jtd-20-284 Text en 2020 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Original Article Wang, Changchun Li, Chengqiang Yang, Xun Mao, Weimin Jiang, Youhua Wu, Jie Zhao, Qiang Ji, Anqi Chen, Qixun Li, Hecheng Liu, Jinshi The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title | The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title_full | The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title_fullStr | The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title_full_unstemmed | The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title_short | The classification and treatment strategies of post-esophagectomy airway-gastric fistula |
title_sort | classification and treatment strategies of post-esophagectomy airway-gastric fistula |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399427/ https://www.ncbi.nlm.nih.gov/pubmed/32802439 http://dx.doi.org/10.21037/jtd-20-284 |
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