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Astragaloside IV sensitizes non-small cell lung cancer cells to cisplatin by suppressing endoplasmic reticulum stress and autophagy

BACKGROUND: Cisplatin is an effective chemotherapeutic drug for treating various cancers including non-small cell lung cancer (NSCLC), but resistance to cisplatin remains the main limitation to its use in clinic. Astragaloside IV (AS-IV), which is derived from Astragalus membranaceus, has been prove...

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Detalles Bibliográficos
Autores principales: Lai, Song-Tao, Wang, Yan, Peng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399439/
https://www.ncbi.nlm.nih.gov/pubmed/32802451
http://dx.doi.org/10.21037/jtd-20-2098