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Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19

BACKGROUND: The spread of the novel coronavirus SARS-CoV-2 and the guidance from authorities for social distancing and media reporting lead to significant uncertainty in Germany. Concerns have been expressed regarding the underdiagnosing of harmful diseases. We explored the rates of emergency presen...

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Autores principales: Schwarz, Viktoria, Mahfoud, Felix, Lauder, Lucas, Reith, Wolfgang, Behnke, Stefanie, Smola, Sigrun, Rissland, Jürgen, Pfuhl, Thorsten, Scheller, Bruno, Böhm, Michael, Ewen, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399595/
https://www.ncbi.nlm.nih.gov/pubmed/32749557
http://dx.doi.org/10.1007/s00392-020-01688-9
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author Schwarz, Viktoria
Mahfoud, Felix
Lauder, Lucas
Reith, Wolfgang
Behnke, Stefanie
Smola, Sigrun
Rissland, Jürgen
Pfuhl, Thorsten
Scheller, Bruno
Böhm, Michael
Ewen, Sebastian
author_facet Schwarz, Viktoria
Mahfoud, Felix
Lauder, Lucas
Reith, Wolfgang
Behnke, Stefanie
Smola, Sigrun
Rissland, Jürgen
Pfuhl, Thorsten
Scheller, Bruno
Böhm, Michael
Ewen, Sebastian
author_sort Schwarz, Viktoria
collection PubMed
description BACKGROUND: The spread of the novel coronavirus SARS-CoV-2 and the guidance from authorities for social distancing and media reporting lead to significant uncertainty in Germany. Concerns have been expressed regarding the underdiagnosing of harmful diseases. We explored the rates of emergency presentations for acute coronary syndrome (ACS) and acute cerebrovascular events (ACVE) before and after spread of SARS-CoV-2. METHODS: We analyzed all-cause visits at a tertiary university emergency department and admissions for ACS and ACVE before (calendar weeks 1–9, 2020) and after (calendar weeks 10–16, 2020) the first coronavirus disease (COVID-19) case in the region of the Saarland, Germany. The data were compared with the same period of the previous year. RESULTS: In 2020 an average of 346 patients per week presented at the emergency department whereas in 2019 an average of 400 patients presented up to calendar week 16 (p = 0.018; whole year 2019 = 395 patients per week). After the first COVID-19 diagnosis in the region, emergency department visit volume decreased by 30% compared with the same period in 2019 (p = 0.0012). Admissions due to ACS decreased by 41% (p = 0.0023 for all; Δ − 71% (p = 0.007) for unstable angina, Δ − 25% (p = 0.42) for myocardial infarction with ST-elevation and Δ − 17% (p = 0.28) without ST-elevation) compared with the same period in 2019 and decreased from 142 patients in calendar weeks 1–9 to 62 patients in calendar weeks 10–16. ACVE decreased numerically by 20% [p = 0.25 for all; transient ischemic attack: Δ − 32% (p = 0.18), ischemic stroke: Δ − 23% (p = 0.48), intracerebral haemorrhage: Δ + 57% (p = 0.4)]. There was no significant change in ACVE per week (p = 0.7) comparing calendar weeks 1–9 (213 patients) and weeks 10–16 (147 patients). Testing of 3756 samples was performed to detect 58 SARS-CoV-2 positive patients (prevalence 1,54%, thereof one patient with myocardial and two with cerebral ischemia) up to calendar week 16 in 2020. CONCLUSIONS: The COVID-19 pandemic was associated with a significant decrease in all-cause admission and admissions due to cardiovascular events in the emergency department. Regarding acute cerebrovascular events there was a numerical decrease but no significant difference.
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spelling pubmed-73995952020-08-04 Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19 Schwarz, Viktoria Mahfoud, Felix Lauder, Lucas Reith, Wolfgang Behnke, Stefanie Smola, Sigrun Rissland, Jürgen Pfuhl, Thorsten Scheller, Bruno Böhm, Michael Ewen, Sebastian Clin Res Cardiol Original Paper BACKGROUND: The spread of the novel coronavirus SARS-CoV-2 and the guidance from authorities for social distancing and media reporting lead to significant uncertainty in Germany. Concerns have been expressed regarding the underdiagnosing of harmful diseases. We explored the rates of emergency presentations for acute coronary syndrome (ACS) and acute cerebrovascular events (ACVE) before and after spread of SARS-CoV-2. METHODS: We analyzed all-cause visits at a tertiary university emergency department and admissions for ACS and ACVE before (calendar weeks 1–9, 2020) and after (calendar weeks 10–16, 2020) the first coronavirus disease (COVID-19) case in the region of the Saarland, Germany. The data were compared with the same period of the previous year. RESULTS: In 2020 an average of 346 patients per week presented at the emergency department whereas in 2019 an average of 400 patients presented up to calendar week 16 (p = 0.018; whole year 2019 = 395 patients per week). After the first COVID-19 diagnosis in the region, emergency department visit volume decreased by 30% compared with the same period in 2019 (p = 0.0012). Admissions due to ACS decreased by 41% (p = 0.0023 for all; Δ − 71% (p = 0.007) for unstable angina, Δ − 25% (p = 0.42) for myocardial infarction with ST-elevation and Δ − 17% (p = 0.28) without ST-elevation) compared with the same period in 2019 and decreased from 142 patients in calendar weeks 1–9 to 62 patients in calendar weeks 10–16. ACVE decreased numerically by 20% [p = 0.25 for all; transient ischemic attack: Δ − 32% (p = 0.18), ischemic stroke: Δ − 23% (p = 0.48), intracerebral haemorrhage: Δ + 57% (p = 0.4)]. There was no significant change in ACVE per week (p = 0.7) comparing calendar weeks 1–9 (213 patients) and weeks 10–16 (147 patients). Testing of 3756 samples was performed to detect 58 SARS-CoV-2 positive patients (prevalence 1,54%, thereof one patient with myocardial and two with cerebral ischemia) up to calendar week 16 in 2020. CONCLUSIONS: The COVID-19 pandemic was associated with a significant decrease in all-cause admission and admissions due to cardiovascular events in the emergency department. Regarding acute cerebrovascular events there was a numerical decrease but no significant difference. Springer Berlin Heidelberg 2020-08-04 2020 /pmc/articles/PMC7399595/ /pubmed/32749557 http://dx.doi.org/10.1007/s00392-020-01688-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Original Paper
Schwarz, Viktoria
Mahfoud, Felix
Lauder, Lucas
Reith, Wolfgang
Behnke, Stefanie
Smola, Sigrun
Rissland, Jürgen
Pfuhl, Thorsten
Scheller, Bruno
Böhm, Michael
Ewen, Sebastian
Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title_full Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title_fullStr Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title_full_unstemmed Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title_short Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
title_sort decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of covid-19
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399595/
https://www.ncbi.nlm.nih.gov/pubmed/32749557
http://dx.doi.org/10.1007/s00392-020-01688-9
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