Cargando…

A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen

Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy. The infant, born at 29 weeks and 6 days of gestati...

Descripción completa

Detalles Bibliográficos
Autores principales: Okada, Yuki, Hitaka, Daisuke, Kido, Takahiro, Kanai, Yu, Konishi, Kumi, Doki, Kosuke, Katayama, Nobuko, Homma, Masato, Miyazono, Yayoi, Takada, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399775/
https://www.ncbi.nlm.nih.gov/pubmed/32774971
http://dx.doi.org/10.1155/2020/2056756
Descripción
Sumario:Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy. The infant, born at 29 weeks and 6 days of gestational age with a birth weight of 1664 g, had no congenital anomalies. This case presents detailed information on the development of an infant with placental transfer of tamoxifen. The infant has grown and developed normally throughout a 5-year follow-up period, but long-term vigilance continues.