Mechanistic studies of cytotoxic activity of the mesoionic compound MIH 2.4Bl in MCF-7 breast cancer cells

In the present study, the cytotoxic effects of a 1,3-thiazolium-5-thiolate derivative of a mesoionic compound, MIH 2.4Bl, were assessed in the MCF-7 breast cancer cell line. The cytotoxic effects of MIH 2.4Bl were determined using a crystal violet assay. Using a dose-response curve, the IC(50) value...

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Detalles Bibliográficos
Autores principales: de Mascena Costa, Luciana Amaral, Debnath, Dipti, Harmon, Ashlyn C., de Sousa Araújo, Silvany, da Silva Souza, Helivaldo Diógenes, de Athayde Filho, Petrônio Filgueiras, Wischral, Aurea, Adrião Gomes Filho, Manoel, Mathis, J. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399858/
https://www.ncbi.nlm.nih.gov/pubmed/32782546
http://dx.doi.org/10.3892/ol.2020.11763

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