COLD-PCR Method for Early Detection of Antiviral Drug-Resistance Mutations in Treatment-Naive Children with Chronic Hepatitis B

We investigated Nucleos(t)ide-analogue (NA)-resistance mutations (mt) in 142 treatment-naive children with Chronic Hepatitis B (CHB), using a sensitive co-amplification at lower denaturation temperature (COLD)-PCR with Sanger DNA sequencing. An NA resistance-associated mt in the hepatitis B virus (H...

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Detalles Bibliográficos
Autores principales: Phung, Thuy Thi Bich, Chu, Son Van, Vu, Son Thien, Pham, Hanh Thi, Nguyen, Hang Minh, Nguyen, Hoan Dang, Le, Ngan Thi, Nguyen, Dung Van, Truong, Phuong Thai, Vu, Van Thi Tuong, Nguyen, Anh Thi Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400161/
https://www.ncbi.nlm.nih.gov/pubmed/32708399
http://dx.doi.org/10.3390/diagnostics10070491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400161/
https://www.ncbi.nlm.nih.gov/pubmed/32708399
http://dx.doi.org/10.3390/diagnostics10070491

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