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Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region

Arteriovenous malformations (AVM) are congenital vascular lesions fed by arterial feeders originating from branches of the internal carotid artery (ICA) or vertebrobasilar artery. We experienced unique AVMs arising in the midline Galenic region, receiving blood supply from the ICA/vertebral artery s...

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Autores principales: Yajima, Hirohisa, Shinya, Yuki, Hasegawa, Hirotaka, Shin, Masahiro, Ueki, Keisuke, Kawashima, Mariko, Ishikawa, Osamu, Saito, Nobuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400176/
https://www.ncbi.nlm.nih.gov/pubmed/32679835
http://dx.doi.org/10.3390/diagnostics10070481
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author Yajima, Hirohisa
Shinya, Yuki
Hasegawa, Hirotaka
Shin, Masahiro
Ueki, Keisuke
Kawashima, Mariko
Ishikawa, Osamu
Saito, Nobuhito
author_facet Yajima, Hirohisa
Shinya, Yuki
Hasegawa, Hirotaka
Shin, Masahiro
Ueki, Keisuke
Kawashima, Mariko
Ishikawa, Osamu
Saito, Nobuhito
author_sort Yajima, Hirohisa
collection PubMed
description Arteriovenous malformations (AVM) are congenital vascular lesions fed by arterial feeders originating from branches of the internal carotid artery (ICA) or vertebrobasilar artery. We experienced unique AVMs arising in the midline Galenic region, receiving blood supply from the ICA/vertebral artery systems and the external carotid artery system. We retrospectively reviewed data on eight patients who had an AVM arising in the Galenic region and were treated in the University of Tokyo Hospital between 1990 and 2019. The median age at diagnosis was 62 years. Three cases (38%) presented with obstructive hydrocephalus due to aqueduct obstruction caused by an engorged vein of Galen. In all cases, feeders from dural arteries were present and the vein of Galen was the primary drainer. All patients underwent stereotactic radiosurgery. Five patients were followed for > two years; nidus obliteration was confirmed in one, and > 75% shrinkage was confirmed in three, while one patient died due to hemorrhage. Altogether, AVMs arising in the Galenic region are rare and exhibit several peculiar characteristics including the presence of dural feeders, an older age at presentation and presentation with obstructive hydrocephalus.
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spelling pubmed-74001762020-08-23 Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region Yajima, Hirohisa Shinya, Yuki Hasegawa, Hirotaka Shin, Masahiro Ueki, Keisuke Kawashima, Mariko Ishikawa, Osamu Saito, Nobuhito Diagnostics (Basel) Article Arteriovenous malformations (AVM) are congenital vascular lesions fed by arterial feeders originating from branches of the internal carotid artery (ICA) or vertebrobasilar artery. We experienced unique AVMs arising in the midline Galenic region, receiving blood supply from the ICA/vertebral artery systems and the external carotid artery system. We retrospectively reviewed data on eight patients who had an AVM arising in the Galenic region and were treated in the University of Tokyo Hospital between 1990 and 2019. The median age at diagnosis was 62 years. Three cases (38%) presented with obstructive hydrocephalus due to aqueduct obstruction caused by an engorged vein of Galen. In all cases, feeders from dural arteries were present and the vein of Galen was the primary drainer. All patients underwent stereotactic radiosurgery. Five patients were followed for > two years; nidus obliteration was confirmed in one, and > 75% shrinkage was confirmed in three, while one patient died due to hemorrhage. Altogether, AVMs arising in the Galenic region are rare and exhibit several peculiar characteristics including the presence of dural feeders, an older age at presentation and presentation with obstructive hydrocephalus. MDPI 2020-07-15 /pmc/articles/PMC7400176/ /pubmed/32679835 http://dx.doi.org/10.3390/diagnostics10070481 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yajima, Hirohisa
Shinya, Yuki
Hasegawa, Hirotaka
Shin, Masahiro
Ueki, Keisuke
Kawashima, Mariko
Ishikawa, Osamu
Saito, Nobuhito
Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title_full Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title_fullStr Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title_full_unstemmed Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title_short Peculiar Characteristics of Arteriovenous Malformations Arising in the Galenic Region
title_sort peculiar characteristics of arteriovenous malformations arising in the galenic region
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400176/
https://www.ncbi.nlm.nih.gov/pubmed/32679835
http://dx.doi.org/10.3390/diagnostics10070481
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