Integrated Genomic Analysis of Chromosomal Alterations and Mutations in B-Cell Acute Lymphoblastic Leukemia Reveals Distinct Genetic Profiles at Relapse

The clonal basis of relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is complex and not fully understood. Next-generation sequencing (NGS), array comparative genomic hybridization (aCGH), and multiplex ligation-dependent probe amplification (MLPA) were carried out in matched diagno...

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Detalles Bibliográficos
Autores principales: Forero-Castro, Maribel, Montaño, Adrián, Robledo, Cristina, García de Coca, Alfonso, Fuster, José Luis, de las Heras, Natalia, Queizán, José Antonio, Hernández-Sánchez, María, Corchete-Sánchez, Luis A., Martín-Izquierdo, Marta, Ribera, Jordi, Ribera, José-María, Benito, Rocío, Hernández-Rivas, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400270/
https://www.ncbi.nlm.nih.gov/pubmed/32635531
http://dx.doi.org/10.3390/diagnostics10070455

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