Cargando…

Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions

We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most...

Descripción completa

Detalles Bibliográficos
Autores principales: Gallina, Laura, Savini, Federica, Canziani, Sabrina, Frasnelli, Matteo, Lavazza, Antonio, Scagliarini, Alessandra, Lelli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400346/
https://www.ncbi.nlm.nih.gov/pubmed/32709033
http://dx.doi.org/10.3390/pathogens9070583
_version_ 1783566342494879744
author Gallina, Laura
Savini, Federica
Canziani, Sabrina
Frasnelli, Matteo
Lavazza, Antonio
Scagliarini, Alessandra
Lelli, Davide
author_facet Gallina, Laura
Savini, Federica
Canziani, Sabrina
Frasnelli, Matteo
Lavazza, Antonio
Scagliarini, Alessandra
Lelli, Davide
author_sort Gallina, Laura
collection PubMed
description We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most common viral agents belonging to the family Papillomaviridae, Poxviridae and Herpesviridae which cause skin diseases in cattle. Two specimens were collected from cases clinically diagnosed as papillomatosis and pseudo-LSD. Both skin lesions were shown to harbor more than one viral species. This case report shows, for the first time, co-infection of zoonotic parapoxvirus with bovine papillomavirus and herpesvirus in skin lesions of cattle. In particular, the simultaneous presence of virions morphologically referable to parapoxvirus and papillomavirus confirms that the replication of both viruses in the same lesion can happen and the so-called papillomatosis can bear zoonotic viruses.
format Online
Article
Text
id pubmed-7400346
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-74003462020-08-23 Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions Gallina, Laura Savini, Federica Canziani, Sabrina Frasnelli, Matteo Lavazza, Antonio Scagliarini, Alessandra Lelli, Davide Pathogens Case Report We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most common viral agents belonging to the family Papillomaviridae, Poxviridae and Herpesviridae which cause skin diseases in cattle. Two specimens were collected from cases clinically diagnosed as papillomatosis and pseudo-LSD. Both skin lesions were shown to harbor more than one viral species. This case report shows, for the first time, co-infection of zoonotic parapoxvirus with bovine papillomavirus and herpesvirus in skin lesions of cattle. In particular, the simultaneous presence of virions morphologically referable to parapoxvirus and papillomavirus confirms that the replication of both viruses in the same lesion can happen and the so-called papillomatosis can bear zoonotic viruses. MDPI 2020-07-17 /pmc/articles/PMC7400346/ /pubmed/32709033 http://dx.doi.org/10.3390/pathogens9070583 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Gallina, Laura
Savini, Federica
Canziani, Sabrina
Frasnelli, Matteo
Lavazza, Antonio
Scagliarini, Alessandra
Lelli, Davide
Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title_full Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title_fullStr Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title_full_unstemmed Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title_short Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
title_sort bovine papillomatosis hiding a zoonotic infection: epitheliotropic viruses in bovine skin lesions
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400346/
https://www.ncbi.nlm.nih.gov/pubmed/32709033
http://dx.doi.org/10.3390/pathogens9070583
work_keys_str_mv AT gallinalaura bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT savinifederica bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT canzianisabrina bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT frasnellimatteo bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT lavazzaantonio bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT scagliarinialessandra bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions
AT lellidavide bovinepapillomatosishidingazoonoticinfectionepitheliotropicvirusesinbovineskinlesions