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Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions
We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400346/ https://www.ncbi.nlm.nih.gov/pubmed/32709033 http://dx.doi.org/10.3390/pathogens9070583 |
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author | Gallina, Laura Savini, Federica Canziani, Sabrina Frasnelli, Matteo Lavazza, Antonio Scagliarini, Alessandra Lelli, Davide |
author_facet | Gallina, Laura Savini, Federica Canziani, Sabrina Frasnelli, Matteo Lavazza, Antonio Scagliarini, Alessandra Lelli, Davide |
author_sort | Gallina, Laura |
collection | PubMed |
description | We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most common viral agents belonging to the family Papillomaviridae, Poxviridae and Herpesviridae which cause skin diseases in cattle. Two specimens were collected from cases clinically diagnosed as papillomatosis and pseudo-LSD. Both skin lesions were shown to harbor more than one viral species. This case report shows, for the first time, co-infection of zoonotic parapoxvirus with bovine papillomavirus and herpesvirus in skin lesions of cattle. In particular, the simultaneous presence of virions morphologically referable to parapoxvirus and papillomavirus confirms that the replication of both viruses in the same lesion can happen and the so-called papillomatosis can bear zoonotic viruses. |
format | Online Article Text |
id | pubmed-7400346 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-74003462020-08-23 Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions Gallina, Laura Savini, Federica Canziani, Sabrina Frasnelli, Matteo Lavazza, Antonio Scagliarini, Alessandra Lelli, Davide Pathogens Case Report We describe two cases of skin co-infections with epitheliotropic viruses, detected in two cattle during lumpy skin disease (LSD) surveillance in northern Italy. A diagnostic protocol including different molecular methods as well as negative staining electron microscopy was applied to detect the most common viral agents belonging to the family Papillomaviridae, Poxviridae and Herpesviridae which cause skin diseases in cattle. Two specimens were collected from cases clinically diagnosed as papillomatosis and pseudo-LSD. Both skin lesions were shown to harbor more than one viral species. This case report shows, for the first time, co-infection of zoonotic parapoxvirus with bovine papillomavirus and herpesvirus in skin lesions of cattle. In particular, the simultaneous presence of virions morphologically referable to parapoxvirus and papillomavirus confirms that the replication of both viruses in the same lesion can happen and the so-called papillomatosis can bear zoonotic viruses. MDPI 2020-07-17 /pmc/articles/PMC7400346/ /pubmed/32709033 http://dx.doi.org/10.3390/pathogens9070583 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Gallina, Laura Savini, Federica Canziani, Sabrina Frasnelli, Matteo Lavazza, Antonio Scagliarini, Alessandra Lelli, Davide Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title | Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title_full | Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title_fullStr | Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title_full_unstemmed | Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title_short | Bovine Papillomatosis Hiding a Zoonotic Infection: Epitheliotropic Viruses in Bovine Skin Lesions |
title_sort | bovine papillomatosis hiding a zoonotic infection: epitheliotropic viruses in bovine skin lesions |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400346/ https://www.ncbi.nlm.nih.gov/pubmed/32709033 http://dx.doi.org/10.3390/pathogens9070583 |
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