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Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis
Granulocyte macrophage colony stimulating factor (GM-CSF) is a pro-inflammatory cytokine produced by immune cells. Recent evidence suggests that GM-CSF plays an important role in multiple sclerosis (MS) pathogenesis. We investigated the expression and regulation of GM-CSF in different immune cells i...
Autores principales: | Aram, Jehan, Frakich, Nanci, Morandi, Elena, Alrouji, Mohammed, Samaraweera, Amal, Onion, David, Spendlove, Ian, Colombo, Sergio L., Tanasescu, Radu, Gran, Bruno, Constantinescu, Cris S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400438/ https://www.ncbi.nlm.nih.gov/pubmed/32708498 http://dx.doi.org/10.3390/biomedicines8070226 |
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