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NuRD mediates mitochondrial stress–induced longevity via chromatin remodeling in response to acetyl-CoA level
Mild mitochondrial stress experienced early in life can have beneficial effects on the life span of organisms through epigenetic regulations. Here, we report that acetyl–coenzyme A (CoA) represents a critical mitochondrial signal to regulate aging through the chromatin remodeling and histone deacety...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400466/ https://www.ncbi.nlm.nih.gov/pubmed/32789178 http://dx.doi.org/10.1126/sciadv.abb2529 |