Cargando…

L-Theanine Reduced the Development of Knee Osteoarthritis in Rats via Its Anti-Inflammation and Anti-Matrix Degradation Actions: In Vivo and In Vitro Study

The etiology of osteoarthritis (OA) is multifactorial, with no effective disease-modifying-drugs. L-theanine has been reported to inhibit inflammatory responses in some diseases and this study aimed to investigate the effect of L-theanine on Interleukin-1(IL-1)β-stimulated chondrocytes, and in an in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bai, Hui, Zhang, Zhiheng, Li, Yue, Song, Xiaopeng, Ma, Tianwen, Liu, Chunpeng, Liu, Lin, Yuan, Rui, Wang, Xinyu, Gao, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400703/ https://www.ncbi.nlm.nih.gov/pubmed/32635404 http://dx.doi.org/10.3390/nu12071988

Ejemplares similares

Natural product, bilobalide, improves joint health in rabbits with osteoarthritis by anti-matrix degradation and antioxidant activities
por: Ma, Tianwen, et al.
Publicado: (2022)

Intra-articular Injection of Baicalein Inhibits Cartilage Catabolism and NLRP3 Inflammasome Signaling in a Posttraumatic OA Model
por: Bai, Hui, et al.
Publicado: (2021)

Melatonin Prevents Chondrocyte Matrix Degradation in Rats with Experimentally Induced Osteoarthritis by Inhibiting Nuclear Factor-κB via SIRT1
por: Zhao, Mingchao, et al.
Publicado: (2022)

Combined detection of COMP and CS846 biomarkers in experimental rat osteoarthritis: a potential approach for assessment and diagnosis of osteoarthritis
por: Ma, Tianwen, et al.
Publicado: (2018)

L-Theanine and Immunity: A Review
por: Chen, Shuna, et al.
Publicado: (2023)

Activation of adenosine A3 receptor attenuates progression of osteoarthritis through inhibiting the NLRP3/caspase‐1/GSDMD induced signalling
por: Bai, Hui, et al.
Publicado: (2022)

Tongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
por: Chen, Weijian, et al.
Publicado: (2023)

Liraglutide, a glucagon-like peptide 1 receptor agonist, exerts analgesic, anti-inflammatory and anti-degradative actions in osteoarthritis
por: Meurot, C., et al.
Publicado: (2022)

Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats
por: Ma, Tianwen, et al.
Publicado: (2022)

Physiological Effects of l-Theanine on Drosophila melanogaster
por: Yang, Hui, et al.
Publicado: (2013)

miR-107 affects cartilage matrix degradation in the pathogenesis of knee osteoarthritis by regulating caspase-1
por: Qian, Jiatian, et al.
Publicado: (2021)

Reduced synovial inflammation and inhibition of matrix metalloproteinases explicates anti-osteoarthritis activity of polyherbal formulations
por: Ingale, Dhanashri R., et al.
Publicado: (2018)

L-Theanine Content and Related Gene Expression: Novel Insights into Theanine Biosynthesis and Hydrolysis among Different Tea Plant (Camellia sinensis L.) Tissues and Cultivars
por: Liu, Zhi-Wei, et al.
Publicado: (2017)

Tonoplast-Localized Theanine Transporter CsCAT2 May Mediate Theanine Storage in the Root of Tea Plants (Camellia sinensis L.)
por: Feng, Lin, et al.
Publicado: (2021)

Combined detection of serum CTX‐II and C2C in a rat model of ACLT‐induced osteoarthritis
por: Yu, Fei, et al.
Publicado: (2023)

A Novel Theanine Complex, Mg-L-Theanine Improves Sleep Quality via Regulating Brain Electrochemical Activity
por: Dasdelen, Muhammed Furkan, et al.
Publicado: (2022)

Effects of baicalein on IL-1β-induced inflammation and apoptosis in rat articular chondrocytes
por: Li, Yue, et al.
Publicado: (2017)

Synergistic effects of epigallocatechin gallate and l-theanine in nerve repair and regeneration by anti-amyloid damage, promoting metabolism, and nourishing nerve cells
por: Xie, Xinya, et al.
Publicado: (2022)

The use of cellular matrix in symptomatic knee osteoarthritis
por: Abbassy, Abir Aly, et al.
Publicado: (2020)

Chronic Circadian Rhythm Disturbance Accelerates Knee Cartilage Degeneration in Rats Accompanied by the Activation of the Canonical Wnt/β-Catenin Signaling Pathway
por: Song, Xiaopeng, et al.
Publicado: (2021)

Anti-chondrocyte apoptosis effect of genistein in treating inflammation-induced osteoarthritis
por: Zou, Yang, et al.
Publicado: (2020)

Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery
por: Tchetina, Elena V., et al.
Publicado: (2020)

Gibberellin Increases the Bud Yield and Theanine Accumulation in Camellia sinensis (L.) Kuntze
por: Li, Wei, et al.
Publicado: (2021)

l-Theanine extends lifespan of adult Caenorhabditis elegans
por: Zarse, Kim, et al.
Publicado: (2012)

Cystine and theanine: amino acids as oral immunomodulative nutrients
por: Kurihara, Shigekazu, et al.
Publicado: (2013)

An anti-inflammatory diet intervention for knee osteoarthritis: a feasibility study
por: Cooper, Indiana, et al.
Publicado: (2022)

Anti-inflammatory and anti-osteoarthritis effects of tectorigenin
por: Wang, Cheng-Long, et al.
Publicado: (2017)

Possible synergic action of non-steroidal anti-inflammatory drugs and glucosamine sulfate for the treatment of knee osteoarthritis: a scoping review
por: Veronese, Nicola, et al.
Publicado: (2022)

A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis
por: Alexander, Louie C., et al.
Publicado: (2021)

Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3
por: Aktas, Erdem, et al.
Publicado: (2011)

Acupotomy versus nonsteroidal anti-inflammatory drugs for knee osteoarthritis: Protocol for a systematic review and meta-analysis
por: Zhang, Renpan, et al.
Publicado: (2019)

Development of 13-Cys-BBR as an Agent Having Dual Action of Anti-Thrombosis and Anti-Inflammation
por: Li, Guanyu, et al.
Publicado: (2020)

Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis
por: XU, YING, et al.
Publicado: (2014)

Chicoric acid is a potent anti-atherosclerotic ingredient by anti-oxidant action and anti-inflammation capacity
por: Tsai, Kun-Ling, et al.
Publicado: (2017)

Anti-Stress, Behavioural and Magnetoencephalography Effects of an l-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial
por: White, David J., et al.
Publicado: (2016)

L-Theanine Alleviates IMQ-Induced Psoriasis Like Skin Inflammation by Downregulating the Production of IL-23 and Chemokines
por: Xu, Yaohan, et al.
Publicado: (2021)

Review of the Mechanism of Action for Supartz FX in Knee Osteoarthritis
por: Altman, Roy D., et al.
Publicado: (2016)

The effect of thermal mineral waters on pain relief, physical function and quality of life in patients with osteoarthritis: A systematic review and meta-analysis
por: Ma, Tianwen, et al.
Publicado: (2021)

Pirfenidone attenuates synovial fibrosis and postpones the progression of osteoarthritis by anti-fibrotic and anti-inflammatory properties in vivo and in vitro
por: Wei, Qilu, et al.
Publicado: (2021)

Association between Markers of Synovial Inflammation, Matrix Turnover and Symptoms in Knee Osteoarthritis: A Cross-Sectional Study
por: Yang, Xiaotian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_sein0aue8c150ilhr1odo1fcmj