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Impact of Case Definitions on Efficacy Estimation in Clinical Trials—A Proof-of-Principle Based on Historical Examples
Efficacy estimations in clinical trials are based on case definitions. Commonly, they are a more or less complex set of conditions that have to be fulfilled in order to define a clinical case. In the simplest variant, such a case is identical with a single positive diagnostic test result. Frequently...
Autores principales: | Hahn, Andreas, Frickmann, Hagen, Zautner, Andreas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400704/ https://www.ncbi.nlm.nih.gov/pubmed/32635553 http://dx.doi.org/10.3390/antibiotics9070379 |
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