Cargando…

Targeting complexes of super-enhancers is a promising strategy for cancer therapy

The hyperactivation and overexpression of critical oncogenes is a common occurrence in multiple types of malignant tumors. Recently, the abnormal activation mechanism of an oncogene by a super-enhancer (SE) has attracted significant attention. A series of changes (insertion, deletion, translocation...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Chuqian, Liu, Min, Fan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400756/
https://www.ncbi.nlm.nih.gov/pubmed/32782573
http://dx.doi.org/10.3892/ol.2020.11855