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CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy

Retinoblastoma (RB) is the most common childhood malignant intraocular tumor. The clinical efficacy of vincristine (VCR) in the treatment of RB is severely limited by drug resistance. Here, we found that CD24, a GPI‐anchored protein, was overexpressed in human RB tissues and RB cell lines, and was a...

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Detalles Bibliográficos
Autores principales: Sun, Jie, Feng, Dongju, Xi, Huiyu, Luo, Jiajing, Zhou, Zewei, Liu, Qinghuai, Chen, Yun, Shao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400807/
https://www.ncbi.nlm.nih.gov/pubmed/32394616
http://dx.doi.org/10.1002/1878-0261.12708