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Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project

A proportion of breast cancer cases are attributable to combined modifiable risk factors. The World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) has recently updated the recommendations for cancer prevention and a standard scoring system has been published. The aim of this...

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Autores principales: Barrios-Rodríguez, Rocio, Toledo, Estefanía, Martinez-Gonzalez, Miguel Angel, Aguilera-Buenosvinos, Inmaculada, Romanos-Nanclares, Andrea, Jiménez-Moleón, José Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400833/
https://www.ncbi.nlm.nih.gov/pubmed/32668662
http://dx.doi.org/10.3390/nu12072076
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author Barrios-Rodríguez, Rocio
Toledo, Estefanía
Martinez-Gonzalez, Miguel Angel
Aguilera-Buenosvinos, Inmaculada
Romanos-Nanclares, Andrea
Jiménez-Moleón, José Juan
author_facet Barrios-Rodríguez, Rocio
Toledo, Estefanía
Martinez-Gonzalez, Miguel Angel
Aguilera-Buenosvinos, Inmaculada
Romanos-Nanclares, Andrea
Jiménez-Moleón, José Juan
author_sort Barrios-Rodríguez, Rocio
collection PubMed
description A proportion of breast cancer cases are attributable to combined modifiable risk factors. The World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) has recently updated the recommendations for cancer prevention and a standard scoring system has been published. The aim of this study was to evaluate the association between compliance with the 2018 WCRF/AICR cancer prevention recommendations (Third Expert Report) and the risk of breast cancer in the SUN (“Seguimiento Universidad de Navarra”) prospective cohort. Spanish female university graduates, initially free of breast cancer, were included (n = 10,930). An 8-item score to measure compliance to the recommendations was built: body fat, physical activity, consumption of wholegrains/vegetables/fruit/beans, “fast foods”, red/processed meat consumption, sugar-sweetened drinks consumption, alcohol intake, and breastfeeding. A stratified analysis was conducted according to menopausal status. A non-significant inverse association was observed for overall breast cancer. The inverse association became statistically significant for post-menopausal breast cancer after multivariable adjustment (hazard ratio for > 5 vs. ≤ 3 points = 0.27; 95% CI: 0.08-0.93). The results suggested that the possible inverse association with breast cancer was attributable to the combined effects of the different nutritional and lifestyle components.
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spelling pubmed-74008332020-08-07 Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project Barrios-Rodríguez, Rocio Toledo, Estefanía Martinez-Gonzalez, Miguel Angel Aguilera-Buenosvinos, Inmaculada Romanos-Nanclares, Andrea Jiménez-Moleón, José Juan Nutrients Article A proportion of breast cancer cases are attributable to combined modifiable risk factors. The World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) has recently updated the recommendations for cancer prevention and a standard scoring system has been published. The aim of this study was to evaluate the association between compliance with the 2018 WCRF/AICR cancer prevention recommendations (Third Expert Report) and the risk of breast cancer in the SUN (“Seguimiento Universidad de Navarra”) prospective cohort. Spanish female university graduates, initially free of breast cancer, were included (n = 10,930). An 8-item score to measure compliance to the recommendations was built: body fat, physical activity, consumption of wholegrains/vegetables/fruit/beans, “fast foods”, red/processed meat consumption, sugar-sweetened drinks consumption, alcohol intake, and breastfeeding. A stratified analysis was conducted according to menopausal status. A non-significant inverse association was observed for overall breast cancer. The inverse association became statistically significant for post-menopausal breast cancer after multivariable adjustment (hazard ratio for > 5 vs. ≤ 3 points = 0.27; 95% CI: 0.08-0.93). The results suggested that the possible inverse association with breast cancer was attributable to the combined effects of the different nutritional and lifestyle components. MDPI 2020-07-13 /pmc/articles/PMC7400833/ /pubmed/32668662 http://dx.doi.org/10.3390/nu12072076 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barrios-Rodríguez, Rocio
Toledo, Estefanía
Martinez-Gonzalez, Miguel Angel
Aguilera-Buenosvinos, Inmaculada
Romanos-Nanclares, Andrea
Jiménez-Moleón, José Juan
Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title_full Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title_fullStr Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title_full_unstemmed Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title_short Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project
title_sort adherence to the 2018 world cancer research fund/american institute for cancer research recommendations and breast cancer in the sun project
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400833/
https://www.ncbi.nlm.nih.gov/pubmed/32668662
http://dx.doi.org/10.3390/nu12072076
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