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Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice
The bile acid receptor, TGR5, is a key regulator of glucose homeostasis, but the mechanisms by which TGR5 signaling improves glucose regulation are incompletely defined. In particular, TGR5 has an increasingly appreciated role in liver physiology and pathobiology; however, whether TGR5 signaling wit...
Autores principales: | Holter, Marlena M., Chirikjian, Margot K., Briere, Daniel A., Maida, Adriano, Sloop, Kyle W., Schoonjans, Kristina, Cummings, Bethany P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400836/ https://www.ncbi.nlm.nih.gov/pubmed/32708970 http://dx.doi.org/10.3390/nu12072124 |
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