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Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice

The bile acid receptor, TGR5, is a key regulator of glucose homeostasis, but the mechanisms by which TGR5 signaling improves glucose regulation are incompletely defined. In particular, TGR5 has an increasingly appreciated role in liver physiology and pathobiology; however, whether TGR5 signaling wit...

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Detalles Bibliográficos
Autores principales: Holter, Marlena M., Chirikjian, Margot K., Briere, Daniel A., Maida, Adriano, Sloop, Kyle W., Schoonjans, Kristina, Cummings, Bethany P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400836/
https://www.ncbi.nlm.nih.gov/pubmed/32708970
http://dx.doi.org/10.3390/nu12072124

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