Cargando…

D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats

To characterize the metabolic actions of D-Pinitol, a dietary inositol, in male Wistar rats, we analyzed its oral pharmacokinetics and its effects on (a) the secretion of hormones regulating metabolism (insulin, glucagon, IGF-1, ghrelin, leptin and adiponectin), (b) insulin signaling in the liver an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Navarro, Juan A., Decara, Juan, Medina-Vera, Dina, Tovar, Rubén, Suarez, Juan, Pavón, Javier, Serrano, Antonia, Vida, Margarita, Gutierrez-Adan, Alfonso, Sanjuan, Carlos, Baixeras, Elena, de Fonseca, Fernando Rodríguez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400942/ https://www.ncbi.nlm.nih.gov/pubmed/32650579 http://dx.doi.org/10.3390/nu12072030

Ejemplares similares

Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol
por: Medina-Vera, Dina, et al.
Publicado: (2021)

d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?
por: Medina‐Vera, Dina, et al.
Publicado: (2022)

Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance
por: Medina-Vera, Dina, et al.
Publicado: (2023)

Pharmacokinetics and Endocrine Effects of an Oral Dose of D-Pinitol in Human Fasting Healthy Volunteers
por: Navarro, Juan A., et al.
Publicado: (2022)

Endocrine and Metabolic Impact of Oral Ingestion of a Carob-Pod-Derived Natural-Syrup-Containing D-Pinitol: Potential Use as a Novel Sweetener in Diabetes
por: Navarro, Juan A., et al.
Publicado: (2022)

Ceratonia siliqua L improved cryodamage of asthenozoospermic specimens: An experimental study
por: Javanmard, Fatemeh, et al.
Publicado: (2023)

Evaluation of The Effects of Carob (Ceratonia siliqua L.) Fruits on the Puberty of Rats
por: Kılınç Uğurlu, Aylin, et al.
Publicado: (2023)

Advances in genotyping microsatellite markers through sequencing and consequences of scoring methods for Ceratonia siliqua (Leguminosae)
por: Viruel, Juan, et al.
Publicado: (2018)

Ceratonia siliqua leaves ethanol extracts exert anti-nociceptive and anti-inflammatory effects
por: Alqudah, Abdelrahim, et al.
Publicado: (2022)

Ceratonia siliqua honeys from Morocco: Physicochemical properties, mineral contents, and antioxidant activities
por: El-Haskoury, Redouan, et al.
Publicado: (2017)

Lipid-Lowering Effects of Carob Extracts (Ceratonia siliqua): Proposed Mechanisms and Clinical Importance
por: Nemet, Marko, et al.
Publicado: (2022)

Phytosynthesis of Zinc Oxide Nanoparticles Using Ceratonia siliqua L. and Evidence of Antimicrobial Activity
por: Karmous, Inès, et al.
Publicado: (2022)

Gastroprotective effect of carob (Ceratonia siliqua L.) against ethanol-induced oxidative stress in rat
por: Rtibi, Kaïs, et al.
Publicado: (2015)

Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress
por: Al-Olayan, Ebtesam M., et al.
Publicado: (2016)

Inoculation with selected indigenous mycorrhizal complex improves Ceratonia siliqua’s growth and response to drought stress
por: Jadrane, Issam, et al.
Publicado: (2021)

Aridity Gradients Shape Intraspecific Variability of Morphological Traits in Native Ceratonia siliqua L. of Morocco
por: Kassout, Jalal, et al.
Publicado: (2023)

Erratum to: Ceratonia siliqua pod extract ameliorates Schistosoma mansoni-induced liver fibrosis and oxidative stress
por: Al-Olayan, Ebtesam M., et al.
Publicado: (2017)

Evaluation of Different Extraction Methods on the Phenolic Profile and the Antioxidant Potential of Ceratonia siliqua L. Pods Extracts
por: Mansouri, Fouad El, et al.
Publicado: (2022)

Structural and Physiological Traits of Compound Leaves of Ceratonia siliqua Trees Grown in Urban and Suburban Ambient Conditions
por: Papadopoulou, Sophia, et al.
Publicado: (2023)

Ceratonia siliqua L. Pod Extract: From Phytochemical Characterization to Liposomal Formulation and Evaluation of Behaviour in Cells
por: De Luca, Maria, et al.
Publicado: (2023)

Biological Activities of Ceratonia siliqua Pod and Seed Extracts: A Comparative Analysis of Two Cretan Cultivars
por: Kavvoura, Dafni-Alexandra, et al.
Publicado: (2023)

Human sperm parameter improvement associated with Ceratonia siliqua extract as a cryopreservation supplement after vitrification
por: Farazmand, Tooba, et al.
Publicado: (2023)

Volatiles profiling in Ceratonia siliqua (Carob bean) from Egypt and in response to roasting as analyzed via solid-phase microextraction coupled to chemometrics
por: Farag, Mohamed A., et al.
Publicado: (2017)

Genome‐wide footprints in the carob tree (Ceratonia siliqua) unveil a new domestication pattern of a fruit tree in the Mediterranean
por: Baumel, Alex, et al.
Publicado: (2022)

Evaluation of the glycemic effect of Ceratonia siliqua pods (Carob) on a streptozotocin-nicotinamide induced diabetic rat model
por: Qasem, Mousa A., et al.
Publicado: (2018)

The Aqueous Extract from Ceratonia siliqua Leaves Protects against 6-Hydroxydopamine in Zebrafish: Understanding the Underlying Mechanism
por: Abidar, Sara, et al.
Publicado: (2020)

Hepatoprotective Effect of Carob Pulp Flour (Ceratonia siliqua L.) Extract Obtained by Optimized Microwave-Assisted Extraction
por: Martić, Nikola, et al.
Publicado: (2022)

Biological Activities of Aqueous Extracts from Carob Plant (Ceratonia siliqua L.) by Antioxidant, Analgesic and Proapoptotic Properties Evaluation
por: Ben Ayache, Siwar, et al.
Publicado: (2020)

Supplementation with a Carob (Ceratonia siliqua L.) Fruit Extract Attenuates the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice
por: de la Fuente-Fernández, María, et al.
Publicado: (2020)

Corrosion Inhibition of Carob Pod Pulp (Ceratonia siliqua L.) on Carbon Steel Surface C38 in Hydrochloric Acid
por: Ghazi, I., et al.
Publicado: (2022)

Phytochemical Characterization and Evaluation of Biological Activities of Egyptian Carob Pods (Ceratonia siliqua L.) Aqueous Extract: In Vitro Study
por: Darwish, Wael Sobhy, et al.
Publicado: (2021)

Vicariance Between Cercis siliquastrum L. and Ceratonia siliqua L. Unveiled by the Physical–Chemical Properties of the Leaves’ Epicuticular Waxes
por: Pereira, Rui F. P., et al.
Publicado: (2022)

Carob Extract (Ceratonia siliqua L.): Effects on Dyslipidemia and Obesity in a High-Fat Diet-Fed Rat Model
por: Rašković, Aleksandar, et al.
Publicado: (2023)

Mapping the Primary and Secondary Metabolomes of Carob (Ceratonia siliqua L.) Fruit and Its Postharvest Antioxidant Potential at Critical Stages of Ripening
por: Kyriacou, Marios C., et al.
Publicado: (2021)

Process Optimization of Phytoantioxidant and Photoprotective Compounds from Carob Pods (Ceratonia siliqua L.) Using Ultrasonic Assisted Extraction Method
por: Ayad, Radia, et al.
Publicado: (2022)

Exploring Carob (Ceratonia siliqua L.): A Comprehensive Assessment of Its Characteristics, Ethnomedicinal Uses, Phytochemical Aspects, and Pharmacological Activities
por: Dahmani, Widad, et al.
Publicado: (2023)

Colour Stability, Fatty Acid Profile, and Lipid Oxidation in Meat Stored in Modified Atmosphere Packaging from Light Lambs Fed with Concentrate with Carob Pulp (Ceratonia siliqua L.)
por: Bottegal, Diego Nicolas, et al.
Publicado: (2023)

Anti-Cancer Activity and Phenolic Content of Extracts Derived from Cypriot Carob (Ceratonia siliqua L.) Pods Using Different Solvents
por: Gregoriou, Gregoria, et al.
Publicado: (2021)

Assemblage of indigenous arbuscular mycorrhizal fungi and green waste compost enhance drought stress tolerance in carob (Ceratonia siliqua L.) trees
por: Boutasknit, Abderrahim, et al.
Publicado: (2021)

Ultrasound Assisted Extraction of Polyphenols from Ripe Carob Pods (Ceratonia siliqua L.): Combined Designs for Screening and Optimizing the Processing Parameters
por: Clodoveo, Maria Lisa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7hjjmrpk6ub71ft542v93f7not