Cargando…

Serine protease inhibitor disrupts sperm motility leading to reduced fertility in female mice(†)

Inhibition of the sperm transport process in the female reproductive tract could lead to infertility. We previously showed that a pan-serine protease inhibitor, 4-(2-aminoethyl)benzenesulfonyl fluoride (AEBSF), blocked semen liquefaction in vivo and resulted in a drastic decrease in the number of sp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barton, Brooke E, Rock, Jenna K, Willie, Anna M, Harris, Emily A, Finnerty, Ryan M, Herrera, Gerardo G, Anamthathmakula, Prashanth, Winuthayanon, Wipawee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Contraceptive Special Issue
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401027/ https://www.ncbi.nlm.nih.gov/pubmed/32303757 http://dx.doi.org/10.1093/biolre/ioaa049

Ejemplares similares

Mechanism of semen liquefaction and its potential for a novel non-hormonal contraception(†)
por: Anamthathmakula, Prashanth, et al.
Publicado: (2020)

Tmprss12 is required for sperm motility and uterotubal junction migration in mice(†)
por: Larasati, Tamara, et al.
Publicado: (2020)

High levels of women's satisfaction and compliance with transdermal contraception: results from a European multinational, 6-month study
por: Jakimiuk, AJ, et al.
Publicado: (2011)

Provision of immediate postpartum intrauterine contraception after vaginal birth within a public maternity setting: Health services research evaluation
por: Cooper, Michelle, et al.
Publicado: (2019)

Thirty years of mirena: A story of innovation and change in women’s healthcare
por: Gemzell‐Danielsson, Kristina, et al.
Publicado: (2021)

Telehealth for Contraceptive Services During the COVID-19 Pandemic: Provider Perspectives
por: Rao, Lavanya, et al.
Publicado: (2022)

Combined oral contraceptives containing estradiol valerate vs ethinylestradiol on coagulation: A randomized clinical trial
por: Haverinen, Annina H., et al.
Publicado: (2022)

Provision of long‐acting reversible contraception at surgical abortion—A cross‐sectional nationwide register study
por: Hogmark, Sara, et al.
Publicado: (2021)

Systemic hormonal contraception and risk of venous thromboembolism
por: Heikinheimo, Oskari, et al.
Publicado: (2022)

Effectiveness, safety and overall satisfaction of early postpartum placement of hormonal IUD compared with standard procedure: An open‐label, randomized, multicenter study
por: Lichtenstein Liljeblad, Karin, et al.
Publicado: (2022)

Contraceptive use among women seeking an early induced abortion in Sweden
por: Niemeyer Hultstrand, Jenny, et al.
Publicado: (2023)

One‐year follow up of contraceptive use and pregnancy rates after early medical abortion: Secondary outcomes from a randomized controlled trial of immediate post‐abortion placement of intrauterine devices
por: Hogmark, Sara, et al.
Publicado: (2023)

Testis-specific serine kinase protein family in male fertility and as targets for non-hormonal male contraception
por: Salicioni, Ana M, et al.
Publicado: (2020)

The Na(+) and K(+) transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception
por: Syeda, Shameem Sultana, et al.
Publicado: (2020)

Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice(†)
por: Nozawa, Kaori, et al.
Publicado: (2020)

Prss55 but not Prss51 is required for male fertility in mice
por: Kobayashi, Kiyonori, et al.
Publicado: (2020)

Advances in contraception: vaginal contraceptive rings
por: Al-Haddad, Sara, et al.
Publicado: (2023)

Emerging concepts in male contraception: a narrative review of novel, hormonal and non-hormonal options
por: Service, C. Austin, et al.
Publicado: (2023)

Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm–egg binding
por: Shang, Xuan, et al.
Publicado: (2018)

An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest
por: Fruzzetti, Franca, et al.
Publicado: (2012)

A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB–SPATA22 complex(†)
por: Xu, Yang, et al.
Publicado: (2020)

Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception(†)
por: Faber, Erik B, et al.
Publicado: (2020)

Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoceptor antagonist activity in isolated preparations of rat vas deferens, for translation into a male contraceptive
por: Mathiew, Mitch, et al.
Publicado: (2020)

Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–private drug discovery institute collaboration(†)
por: Balbach, Melanie, et al.
Publicado: (2020)

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction(†)
por: Sun, Jiang, et al.
Publicado: (2020)

The postcoital test in the development of new vaginal contraceptives
por: Mauck, Christine K, et al.
Publicado: (2020)

The role of team science in the future of male contraception
por: Vahdat, Heather L, et al.
Publicado: (2020)

Exogenous sex steroids regulate genital epithelial barrier function in female rhesus macaques
por: Quispe Calla, Nirk E, et al.
Publicado: (2020)

CIB4 is essential for the haploid phase of spermatogenesis in mice
por: Xu, Zoulan, et al.
Publicado: (2020)

Engineering monoclonal antibody-based contraception and multipurpose prevention technologies(†)
por: Anderson, Deborah J, et al.
Publicado: (2020)

HIV, progestins, genital epithelial barrier function, and the burden of objectivity
por: Vicetti Miguel, Rodolfo D, et al.
Publicado: (2020)

The new contraceptive revolution: developing innovative products outside of industry(†,‡)
por: Callahan, Rebecca L, et al.
Publicado: (2020)

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity
por: Park, Soojin, et al.
Publicado: (2020)

Retinoic acid receptor antagonists for male contraception: current status(†)
por: Noman, Md Abdullah Al, et al.
Publicado: (2020)

Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice
por: Devlin, Darius J, et al.
Publicado: (2020)

Development of multipurpose technologies products for pregnancy and STI prevention: update on polyphenylene carboxymethylene MPT gel development(†)
por: Weitzel, Mary, et al.
Publicado: (2020)

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis
por: Hanna, Carol B, et al.
Publicado: (2020)

Towards a roadmap to advance non-hormonal contraceptive multipurpose prevention technologies: strategic insights from key stakeholders(†)
por: Hemmerling, Anke, et al.
Publicado: (2020)

Filamentous actin disorganization and absence of apical ectoplasmic specialization disassembly during spermiation upon interference with retinoid signaling(†)
por: Chung, Sanny S W, et al.
Publicado: (2020)

Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes
por: Li, Feng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qomgoit0bhdh1aqrfo7u81luqq