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Pterostilbene reduces endothelial cell apoptosis by regulation of the Nrf2-mediated TLR-4/MyD88/NF-κB pathway in a rat model of atherosclerosis

Endothelial cell injury in vascular arterial walls plays a crucial role in the pathological process of atherosclerosis. Pterostilbene, a stilbenoid chemically related to resveratrol, has anti-inflammatory, anti-apoptosis and antioxidant properties. However, the underlying mechanisms mediated by pter...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaowei, Lu, Weihang, Zhang, Kaihua, Zhou, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401285/
https://www.ncbi.nlm.nih.gov/pubmed/32782521
http://dx.doi.org/10.3892/etm.2020.8923

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